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On the Department from Epidemiology, Service away from Medication (M.A beneficial.Meters., T.Grams., Meters.Meters.) and you will Department from Nutrition and you will Integrative Anatomy (P.Yards.Grams.), University regarding Utah, Sodium River Town; Service out of Treatments, Ny College or university College from Medicine (J.Meters.B.); Welch Center having Prevention, Epidemiology and you can Systematic Search, Johns Hopkins College, Baltimore, MD (L.J.A good.); and Institution out-of Biostatistical Sciences, Aftermath Forest School of Drug, Winston-Salem, NC (J.A.T.).
You are enjoying the most up-to-date variety of this short article. Earlier versions:
Throughout the Department out-of Epidemiology, Service off Medication (Yards.A.Meters., T.Grams., Meters.Meters.) and you will Agencies from Nutrients and you may Integrative Physiology (P.Yards.Grams.), University of Utah, Sodium Lake Town; Company regarding Treatments, Ny College or university College or university regarding Medicine (J.M.B.); Welch Center getting Reduction, Epidemiology and you may Systematic Research, Johns Hopkins College, Baltimore, MD (L.J.A great.); and Department regarding Biostatistical Sciences, Aftermath Forest University away from Treatments, Winston-Salem, NC (J.A great.T.).
You’re seeing the newest variety of this short article. Earlier versions:
Regarding the Office from Epidemiology, Institution out of Medicine (Yards.Good.Meters., T.Grams., Yards.M.) and you can Company out of Nutrients and you can Integrative Structure (P.M.Grams.), College or university off Utah, Sodium River Urban area; Service away from Medicine, Nyc College University out of Medicine (J.Yards.B.); Welch Heart having Avoidance, Epidemiology and Health-related Search, Johns Hopkins University, Baltimore, MD (L.J.A beneficial.); and you may Service out-of Biostatistical Sciences, Aftermath Tree University from Medication, Winston-Salem, NC (J.Good.T.).
You’re seeing the newest sorts of this post. Earlier incarnations:
About Office of Epidemiology, Institution regarding Drug (Meters.A great.Yards., T.G., M.Meters.) and you can Department from Nutrients and you may Integrative Structure (P.M.G.), School away from Utah, Sodium River Area; Agencies of Medication, New york College or university School out-of Medication (J.Yards.B.); Welch Center to have Reduction, Epidemiology and you will Scientific Lookup, Johns Hopkins College or university, Baltimore, MD (L.J.An excellent.); and you can Institution off Biostatistical Sciences, Wake Forest University of Drug, Winston-Salem, NC (J.A great.T.).
You are viewing the newest variety of this information. Earlier incarnations:
In the Department out-of Epidemiology, Agency out-of Treatments (M.An effective.M., T.Grams., M.Meters.) and you can Department from Nutrients and you can Integrative Structure (P.Meters.G.), University off Utah, Salt River Area; Agencies regarding Medicine, New york College or university School away from Treatments (J.Meters.B.); Welch Heart to possess Prevention, Epidemiology and you can Clinical Look, Johns Hopkins School, Baltimore, MD (L.J.A good.); and you can Agencies of Biostatistical Sciences, Wake Tree College out-of Treatments, Winston-Salem, NC (J.A great.T.).
You are watching the most recent brand of this information. Earlier versions:
About Section out of Epidemiology, Agency away from Drug (Meters.A beneficial.Yards., T.G., Yards.Meters.) and Institution out of Diet and Integrative Structure (P.Yards.Grams.), College of Utah, Sodium River Urban area; Company away from Medicine, Nyc College School from Drug (J.Meters.B.); Welch Heart having Avoidance, Epidemiology and you will Medical Look, Johns Hopkins University, Baltimore, MD (L.J.A beneficial.); and you may Institution off Biostatistical Sciences, Wake Tree College from Medication, Winston-Salem, NC (J.A.T.).
You are watching the most up-to-date brand of this informative article. Previous versions:
On Section out of Epidemiology, Company out-of Medicine (Yards.A.M., T.Grams., M.M.) and you will Agencies away from Diet and you will Integrative Physiology (P.Meters.Grams.), College off Utah, Salt River Town; Agencies away from Drug, New york College School away from Treatments (J.Meters.B.); Welch Cardiovascular system to have Prevention, Epidemiology and you can Scientific Browse, Johns Hopkins University, Baltimore, MD (L.J.A great.); and you can Agency off Biostatistical Sciences, Wake Forest School out of Medicine, Winston-Salem, NC (J.Good.T.).
Abstract
Dietary Na recommendations are expressed as absolute amounts (mg/d) rather than as Na density (mg/kcal). Our objective was to determine whether the strength of the relationship of Na intake with blood pressure (BP) varied with energy intake. The DASH (Dietary Approaches to Stop Hypertension)–Sodium trial was a randomized feeding trial comparing 2 diets (DASH and control) and 3 levels of Na density. Participants with pre- or stage 1 hypertension consumed diets for 30 days in random order; energy intake was controlled to maintain body weight. This secondary analysis of 379 non-Hispanic black and white participants used mixed-effects models to assess the association of Na and energy intakes with BP. The relationships between absolute Na and both systolic silverdaddies and diastolic BP varied with energy intake. BP rose more steeply with increasing Na at lower energy intake than at higher energy intake (P interaction<0.001). On the control diet with 2300 mg Na, both systolic and diastolic BP were higher (3.0 mm Hg; 95% confidence interval, 0.2–5.8; and 2.7 mm Hg; 95% confidence interval, 1.0–4.5, respectively) among those with lower energy intake (higher Na density) than among those with higher energy intake (lower Na density). The association of Na with systolic BP was stronger at lower levels of energy intake in both blacks and whites (P<0.001). The association of Na and diastolic BP varied with energy intake only among blacks (P=0.001). Sodium density should be considered as a metric for expressing dietary Na recommendations.